Hi Dave welcome t the forum from Plmouth UK we are a sort of multi national bunch here on the forum
How heavily stocked is your 220 gallon pond please how many of each fish mentioned by you do you have?
Firstly can you tell us your water perameters please Ammonia, Nitrite Nitrate, Ph, Kh what maintenance you do on your pond water changes filtermaintenance etc
Sadly its easy to jump to conclusions that these are ulcers and are caused by bad water conditions, but this could even be a very bad case of sunburn (yes fish can get sunburn) .
However in our 27 years of koi keeping Val and I have only ever come across wounds in the place that they are, once and that was in our friend Kev's tropical fish tank.
But what in our veiw this most probably is does effect coldwater fishes as well as tropical and marine fish.
Weve a feeling that what we are looking at is called HLLE or Head and Lateral Line Erosion commonly know in laymans terms as Hole in the Head disease, from what I can remember about it from my friends outbreak is this, It's a little know disease which the experts say the causes of remain unlear but infection by a flagellate protozaons Hexamita or Spironucleus have been thought of as a cause.
Bacterial infection, over crowding, poor water conditions unhygenic conditions , low oxygen levels in the pond ,inadiquate Nutrition , could well be a factor in your outbreak so dont be offened we all have to learn sometimes the hard way .
What to do First off we need your water perameters and to set about fixing things if they are a mess.
Next you need to get airstones into the pond, to add oxygen into the water thus getting rid of any low oxygen conditions you may have ( I doubt you have a drop kit to tell us what they levels are perchance)?
You need throw away the food you have now and buy new, pellet form is better than that of flake food (keep in a sealed container and mark the best before date on the container (do not use after that date) try soaking the pellets in orange juice to give them vitamin C from time to time. or like us put a half an orange in the pond , our own koi make very short work of a half an orange when we offer it to them
Feed your fish Medicated food if your from the UK the only source of this is from vets or NTLabs medicated koi food,
There are a few drugs you could use but these are only available from the vet they are dimetridazole and metronidazole they will need several applications of the drug ask a vet to help you with this (sadly its going to cost you )..
The only way to avoid this disease in future is to Quarentine your fish in a QT fasility for around 2 months , and to illiminate any of the factors I mention in this post .
They do respond quite well to treatment, please keep us all posted on how you get on as I know everyone wishes to see your fish cured
Dave
Note:-" I'm not suggesting you dont know anything about fish keeping" but Kev was a youngster who didnt have a clue about fish keeping who tried to run before he could walk and the reason why he had his outbreak, so I strongly suggest you buy a book on fish health and take its contents to your heart if you dont wish a repeat please see our list of books from our library these books are available quite cheaply on Amazon books :-
https://www.gardenpondforum.com/threads/our-fish-koi-health-library-with-reviews-of-each-book.10498/
Also read our thread about vitamins it will help you in the future :-
https://www.gardenpondforum.com/thr...ects-on-our-koi-and-the-answer-to-this.11001/